How much radiologically isolated syndrome suggestive of multiple sclerosis is multiple sclerosis?

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How much radiologically isolated syndrome suggestive of multiple sclerosis is multiple sclerosis?

In spite of the progress in Neuroimmunology, a specific biomarker for the diagnosis of multiple sclerosis (MS) remains to be defined. Meanwhile, as growing enthusiasm has been associated with the development of new therapeutic options and the recent evidence that the disease-modifying agents may be more beneficial for MS patients if initiated as early as possible following disease onset1, inves...

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Improving the Characterization of Radiologically Isolated Syndrome Suggestive of Multiple Sclerosis

OBJECTIVE To improve the characterization of asymptomatic subjects with brain magnetic resonance imaging (MRI) abnormalities highly suggestive of multiple sclerosis (MS), a condition named as "radiologically isolated syndrome" (RIS). METHODS Quantitative MRI metrics such as brain volumes and magnetization transfer (MT) were assessed in 19 subjects previously classified as RIS, 20 demographica...

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Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome.

BACKGROUND The discovery and broad application of MRI in medicine has led to an increased awareness in the number of patients with incidental white matter pathology in the CNS. Routinely encountered in clinical practice, the natural history or evolution of such individuals with respect to their risk of developing multiple sclerosis (MS) is unclear. OBJECTIVE To investigate the natural history...

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Conversion from Radiologically Isolated Syndrome to Multiple Sclerosis

BACKGROUND The aim of this study was to estimate the conversion rate from radiologically isolated syndrome (RIS) to definite multiple sclerosis (MS). METHODS During a mean (standard deviation [SD]) follow-up period of 17.4 (5.4) (range 8-29) months, 25 subjects with RIS and without neurological symptom aged 22-45 year from a single-center have been examined for the occurrence of definite MS. ...

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conversion from radiologically isolated syndrome to multiple sclerosis

background: the aim of this study was to estimate the conversion rate from radiologically isolated syndrome (ris) to definite multiple sclerosis (ms). methods: during a mean (standard deviation [sd]) follow-up period of 17.4 (5.4) (range 8-29) months, 25 subjects with ris and without neurological symptom aged 22-45 year from a single-center have been examined for the occurrence of definite ms. ...

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ژورنال

عنوان ژورنال: Arquivos de Neuro-Psiquiatria

سال: 2012

ISSN: 0004-282X

DOI: 10.1590/s0004-282x2012000100002